Conduct Disorder is the key paediatric and adolescent disorder characterized by severe aggression. Our understanding of the neurobiology to subtype aggression and callous unemotional traits (CU) is limited. MATRICS focuses on the subtyping of aggression and CU – from preclinical research to treatment. To find out more about the project, click here.

In an interview conducted at the 30^th ECNP Congress in Paris in September 2017, the project's scientific coordinator, Dr. Jeffrey Glennon, explains the medical, societal and scientific need to understand the underlying mechanisms of aggression, and how the MATRICS consortium aims to develop better prevention and intervention strategies as well as novel pharmacotherapy to treat juvenile conduct syndromes and aggressive behaviours more effectively.