Full
Aims & Objectives

The overarching goal of the MATRICS proposal is to test the key hypothesis that different aggression phenotypes result from differential impairment of arousal mechanisms which in turn dysregulates three basic neural functions: regulation of control mechanisms of aggression, emotional value rating of others, and empathy and moral decision making.

Thus, we propose to deconstruct current classifications of aggression phenotypes into these three neural systems that are coupled with hypo- and hyper-arousal mechanisms.

To study these functions, we employ the same psychological tasks in both animal aggression models and human disruptive behavior disorders samples concurrent with the assessment of neural, neurochemical, genetic, autonomic nervous system and endocrinologic markers.

Top
This website uses cookies to improve your experience. We'll assume you're ok with this, but you can opt-out if you wish. Until you give your consent, only those cookies necessary to maintain the website's functionality are active. When you choose "OK", so called third-party non-functional cookies (e.g. GDPR-conform Google Analytics) may also become active. Please be aware that the website's functionality may be restricted if you choose "DECLINE". You can revoke your choice at any time by clearing your browser cache/history and updating your selection. Please also view our privacy policy.
Ok Decline